2-Chloro-6-3-1, 1-dimethyl-2-(2-naphthyl)ethylamino-2(R)-hydroxypropoxy benzonitrile

2-Chloro-6-3-1, 1-dimethyl-2-(2-naphthyl)ethylamino-2(R)-hydroxypropoxy benzonitrile

Product name:2-Chloro-6-[3-[1, 1-dimethyl-2-(2-naphthyl)ethylamino]-2(R)-hydroxypropoxy]benzonitrile

CAS:284035-33-2

Molecular Formula:C24H25ClN2O2

Formula Weight:408.92g/mol

Description:It is the prototype calcilytic drug, designed to not on calcium receptors on the surface of parathyroid glands, stimulating the release of the body's own stores of native parathyroid hormone (PTH). In osteopenic ovariectomized rats, daily oral administration of NPS-3143 resulted in moderate but sustained increases in plasma PTH levels and marked increases in bone formation and resorption, with no net bone gain or loss.

 

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