Product name:AZD1152-HQPA
CAS:722544-51-6
Description:AZD1152-HQPA is a highly potent and selective inhibitor of Aurora B (Ki, 0.36 nmol/L) compared with Aurora A (Ki, 1,369 nmol/L) and has a high specificity versus a panel of 50 other kinases (13).Consistent with inhibition of Aurora B kinase, addition of AZD1152-HQPA to tumor cells in vitro induces chromosome misalignment, prevents cell division, and consequently reduces cell viability and induces apoptosis (13).