Product name:CP 690550
CAS:477600-75-2
Molecular Formula:C16H20N6O
Formula Weight:312.3696g/mol
Description:Janus kinase 3 (JAK3) is a cytoplasmic tyrosine kinase associated with the common chain, an integral component of cytokine receptors of the interleukin (IL)-2 family, including IL-4, -7, -9, -15, and -21. CP-690550 is a JAK3 inhibitor with immunosuppressive properties under development for transplantation.IL-15 is important for maintaining homeostasis of these cell types, and CP-690550 inhibited IL-15-induced CD69 expression in NK cells.