Diprophylline

Diprophylline

Product name:Diprophylline
CAS: 479-18-5
Molecular Formula: C10H14N4O4
Molecular Weight: 254.24
Product description:This product is white powder or granular; Odourless, taste bitter. This product soluble in water, slightly soluble in ethanol, slightly dissolved in chloroform or ether.This product and asthma effects similar to those of theophylline. The heart excitation of aminophylline only 1/20 ~ 1/10. Less impact on the heart and nervous system. Especially suitable for asthma patients with tachycardia. This product has directly on airway smooth muscle relaxation effect, its mechanism is complex, used to think that by inhibiting phosphodiesterase, caused by intracellular CAMP levels increase. Recent experiments that theophylline bronchiectasis effect is partly due to endogenous epinephrine and norepinephrine released as a result, in addition, theophylline is purine receptor blockers, can fight the constriction of adenine on the respiratory tract. Theophylline can enhance diaphragmatic muscle contraction force, especially in the diaphragm of contracting effect is more significant. Therefore help to improve the respiratory function.

 

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