Mafenide

Product name:Mafenide
CAS: 138-39-6
Molecular Formula: C7H10N2O2S
Molecular Weight: 186.22
Product description:Wide antimicrobial spectrum, for a variety of gram negative and positive, has strong effect to pseudomonas aeruginosa. From the pus pseudomonas aeruginosa Pseudomonas aeruginosa , necrotic tissue, influence on ammonia acid and so on, and can quickly penetrate into the wound and eschar, so local applied to burn infection and festering wounds are more appropriate. The disadvantage is that: the local can appear when pain, burning sensation, sometimes may cause allergic reactions. When it is applied in a large wound, unfavorable use its hydrochloride, otherwise acidemia may be produced, then to adopt the acetate is advisable. In e. coli, tetanus bacillus, bacillus subtilis, staphylococcus aureus, hemolytic streptococcus, streptococcus pneumoniae, etc also have certain effect, but quickly inactivated in the blood, reason for topical application only, is generally not used for oral and injection.

 

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