Product name:Minocycline
CAS: 10118-90-8
Molecular Formula: C23H27N3O7
Molecular Weight: 457.48
Product description:Antibacterial agent has broad-spectrum antibacterial function for quick. Mechanism with aminoglycoside, drugs by the cell's outer membrane protein OmpF and OmpC diffusion through the cell membrane and energy dependence on transfer system into the cell, with A 30 s ribosomal subunits on specific binding, prevent amino acid - tRNA and ribosomes, thus inhibiting peptide chain extension and protein synthesis. Tetracyclines can combine with the 70 s ribosomal with mitochondria, inhibition of mitochondrial protein synthesis, tetracycline effect on some species may be associated with this role. High concentrations of drugs on certain bacteria has the effects of sterilization. Bacteria to tetracycline class of cross resistance between each type. The main resistance mechanism to active efflux system, drug will excrete bacteria; Second to produce a protein that helps protect the ribosome, ribosomes make combination with drugs can't; Occasionally the drug-resistant bacteria can produce drug degradation enzymes, drug inactivated. Mainly through its resistance plasmid mediated by resistant plasmid transfer sensitive bacteria resistant.